&lt;h2&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;Overview&lt;/strong&gt;&lt;/span&gt;&lt;/h2&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400; color: #808080;&quot;&gt;The Actin, Smooth Muscle (SMActin) Immunostain, Technical Component Only, is used to detect cells expressing the alpha-smooth muscle isoform of actin. Reflex tests include IHTOI for both initial and additional technical components, which are automatically triggered and billed. The method utilized is Immunohistochemistry (IHC). Specimens required are tissue samples, collected in an Immunostain Technical Only Envelope.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400; color: #808080;&quot;&gt;The test solely involves the technical execution of the stain, with no interpretation by a pathologist. Shipping instructions advise affixing provided labels onto the transport container. Rejection criteria include wet/frozen tissue, cytology smears, and non-formalin-fixed or non-paraffin-embedded tissue. Specimen stability information depends on storage conditions.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;hr /&gt;
&lt;h3&gt;&amp;nbsp;&lt;/h3&gt;
&lt;h3&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;WHAT IS IT USED FOR?&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400; color: #808080;&quot;&gt;Detection of cells that express the alpha-smooth muscle isoform of actin.&lt;/span&gt;&lt;/p&gt;

&lt;h3&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;REFLEX TESTS&amp;nbsp;&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;ul&gt;
&lt;li style=&quot;font-weight: 400;&quot; aria-level=&quot;1&quot;&gt;&lt;span style=&quot;color: #808080;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;IHTOI &lt;/span&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;&amp;ndash; &lt;/span&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;IHC Initial, Tech Only&lt;/span&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt; &amp;ndash; (Not Available Separately), (Not Always Performed)&lt;/span&gt;&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot; aria-level=&quot;1&quot;&gt;&lt;span style=&quot;color: #808080;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;IHTOI &lt;/span&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;&amp;ndash; &lt;/span&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;IHC Additional, Tech Only&lt;/span&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt; &amp;ndash; (Not Available Separately), (Not Always Performed)&lt;/span&gt;&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;h3&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;TESTING ALGORITHM&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400; color: #808080;&quot;&gt;If only the initial technical component involves immunohistochemical (IHC) staining, the corresponding bill-only test ID (IHTOI) will be automatically triggered and billed. Similarly, for each additional technical component solely involving IHC staining, an extra bill-only test ID (IHTOA) will be reflexively activated and charged.&lt;/span&gt;&lt;/p&gt;
&lt;h3&gt;&amp;nbsp;&lt;/h3&gt;
&lt;h3&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;METHOD NAME&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400; color: #808080;&quot;&gt;Immunohistochemistry (IHC)&lt;/span&gt;&lt;/p&gt;
&lt;h3&gt;&amp;nbsp;&lt;/h3&gt;
&lt;h3&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;AVAILABILITY&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400; color: #808080;&quot;&gt;TBC&lt;/span&gt;&lt;/p&gt;
&lt;h3&gt;&amp;nbsp;&lt;/h3&gt;
&lt;h3&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;REPORTING NAME&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;h4&gt;&lt;span style=&quot;font-weight: 400; color: #808080;&quot;&gt;Actin, smooth muscle IHC, Tech Only&lt;/span&gt;&lt;/h4&gt;
&lt;h3&gt;&amp;nbsp;&lt;/h3&gt;
&lt;h3&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;ALIASES&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400; color: #808080;&quot;&gt;SMActin&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400; color: #808080;&quot;&gt;ISSMACNIHCTO&lt;/span&gt;&lt;/p&gt;
&lt;h3&gt;&amp;nbsp;&lt;/h3&gt;
&lt;h3&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;SPECIMEN TYPE&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;h4&gt;&lt;span style=&quot;font-weight: 400; color: #808080;&quot;&gt;TECHONLY&lt;/span&gt;&lt;/h4&gt;
&lt;h3&gt;&amp;nbsp;&lt;/h3&gt;
&lt;h3&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;ORDERING GUIDANCE&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400; color: #808080;&quot;&gt;This test solely encompasses the technical execution of the stain, without any interpretation by a pathologist. If there&#39;s a need for diagnostic consultation by a pathologist, please request PATHC / Pathology Consultation.&lt;/span&gt;&lt;/p&gt;
&lt;h3&gt;&amp;nbsp;&lt;/h3&gt;
&lt;h3&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;SHIPPING INSTRUCTIONS&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400; color: #808080;&quot;&gt;Affix the green pathology address label and the pink Immunostain Technical Only label provided in the kit onto the exterior of the transport container.&lt;/span&gt;&lt;/p&gt;
&lt;h3&gt;&amp;nbsp;&lt;/h3&gt;
&lt;h3&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;SPECIMEN REQUIRED&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400; color: #808080;&quot;&gt;Supplies: Immunostain Technical Only Envelope (T693)&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400; color: #808080;&quot;&gt;Specimen Type: Tissue&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400; color: #808080;&quot;&gt;Container/Tube: Immunostain Technical Only Envelope&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400; color: #808080;&quot;&gt;Preferred: 2 Unstained positively charged glass slide (25- x 75- x 1-mm) per test ordered; sections 4-microns thick.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400; color: #808080;&quot;&gt;Acceptable: Formalin-fixed, paraffin-embedded (FFPE) tissue block&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;h3&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;REJECT DUE TO&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;ul&gt;
&lt;li style=&quot;font-weight: 400;&quot; aria-level=&quot;1&quot;&gt;&lt;span style=&quot;font-weight: 400; color: #808080;&quot;&gt;Wet/frozen tissue&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot; aria-level=&quot;1&quot;&gt;&lt;span style=&quot;font-weight: 400; color: #808080;&quot;&gt;Cytology smears&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot; aria-level=&quot;1&quot;&gt;&lt;span style=&quot;font-weight: 400; color: #808080;&quot;&gt;Nonformalin fixed tissue&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot; aria-level=&quot;1&quot;&gt;&lt;span style=&quot;font-weight: 400; color: #808080;&quot;&gt;Nonparaffin-embedded tissue&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot; aria-level=&quot;1&quot;&gt;&lt;span style=&quot;font-weight: 400; color: #808080;&quot;&gt;Noncharged slides&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot; aria-level=&quot;1&quot;&gt;&lt;span style=&quot;font-weight: 400; color: #808080;&quot;&gt;ProbeOn slides&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;
&lt;h3&gt;&amp;nbsp;&lt;/h3&gt;
&lt;h3&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;SPECIMEN STABILITY INFORMATION&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;ul&gt;
&lt;li style=&quot;font-weight: 400;&quot; aria-level=&quot;1&quot;&gt;&lt;span style=&quot;color: #808080;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;TECHONLY &lt;/span&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;&amp;ndash; &lt;/span&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Ambient (preferred)&lt;/span&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt; &amp;ndash; TBC days&lt;/span&gt;&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot; aria-level=&quot;1&quot;&gt;&lt;span style=&quot;color: #808080;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;TECHONLY &lt;/span&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;&amp;ndash; &lt;/span&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Refrigerated &lt;/span&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;&amp;ndash; TBC days&lt;/span&gt;&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;